Idiopathic scrotal calcinosis: A case report of a long-standing scrotal mass

Abstract

Idiopathic scrotal calcinosis (ISC) is a rare, benign disorder characterized by multiple calcified nodules within the 
scrotal dermis in the absence of abnormalities of calcium or phosphate metabolism. Although described more than 
a century ago, its etiopathogenesis remains controversial, with debate regarding dystrophic calcification of cysts 
versus a truly idiopathic origin. We report a case of a 58-year old male presenting with a progressively enlarging, 
painless, multinodular scrotal swelling of 15 years duration. All nodules were surgically excised, the largest measuring 3 × 3 × 2 cm, while the remaining lesions were smaller. Gross examination revealed multiple chalky-white areas. Histopathologically, amorphous basophilic calcific deposits surrounded by foreign-body giant cell reaction and chronic inflammatory infiltrate, without identifiable epithelial lining, confirmed the diagnosis of ISC. The patient remained asymptomatic with no recurrence on follow-up. Histopathological evaluation is essential for definitive diagnosis, and complete surgical excision is curative with excellent prognosis.