Skin mediated human papillomavirus infection in breast: A report of four cases

Authors

  • Saimul Islam
  • Hemantika Dasgupta
  • Mukta Basu
  • Anup Roy
  • Neyaz Alam
  • Gautam Kumar Mandal
  • Susanta Roychoudhury
  • Chinmay Kumar Panda

DOI:

https://doi.org/10.32677/ijcr.v4i2.792

Keywords:

Breast cancer, breast skin, E6/E7 oncoproteins, human papillomavirus, human papillomavirus transmission

Abstract

To address the ambiguity of different modes of human papillomavirus (HPV) transmission in breast, the immunohistochemical expression of two oncoproteins E6/E7 of HPV16 was analyzed in primary breast cancer (BC) and adjacent normal skin of 4 samples. The patients were of 35–55 years old having no previous history of cancer. The E6/E7 expressions were evident in both skin and BC. In skin, high/moderate cytoplasmic expressions of E6/E7 proteins were seen in all samples, whereas in BC, high/moderate cytoplasmic expressions of the proteins were observed in 2–3 samples. Thus, it seems that HPV infection in the breast may occur through the skin.

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Published

2018-03-23

Issue

Vol. 4 No. 2 (2018): March - April

Section

Case Report

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

Skin mediated human papillomavirus infection in breast: A report of four cases (S. Islam, H. Dasgupta, M. Basu, A. Roy, N. Alam, G. K. Mandal, S. Roychoudhury, & C. K. Panda, Trans.). (2018). Indian Journal of Case Reports, 4(2), 98-102. https://doi.org/10.32677/ijcr.v4i2.792